Bluetongue

Todayโ€™s path rounds are on ๐›๐ฅ๐ฎ๐ž๐ญ๐จ๐ง๐ ๐ฎ๐ž!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐๐ฅ๐ฎ๐ž๐ญ๐จ๐ง๐ ๐ฎ๐ž is a viral infection, caused by ๐›๐ฅ๐ฎ๐ž๐ญ๐จ๐ง๐ ๐ฎ๐ž ๐ฏ๐ข๐ซ๐ฎ๐ฌ. The virus gets its name because it can cause ๐œ๐ฒ๐š๐ง๐จ๐ฌ๐ข๐ฌ (blue tinge to the tissue) of the tongue! Weird.

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
This disease affects ruminants!

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
Bluetongue virus is transmitted by ๐›๐ข๐ญ๐ข๐ง๐  ๐ฆ๐ข๐๐ ๐ž๐ฌ. The midge feeds on an infected animal, acquiring the virus. The midge then deposits the virus in the next animal it feeds on. Some strains of bluetongue virus may also spread by direct contact between animals.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
Bluetongue virus characteristically damages ๐ž๐ง๐๐จ๐ญ๐ก๐ž๐ฅ๐ข๐š๐ฅ ๐œ๐ž๐ฅ๐ฅ๐ฌ, which are the cells that line blood vessels. This results in a ๐ฏ๐š๐ฌ๐œ๐ฎ๐ฅ๐ข๐ญ๐ข๐ฌ (inflammation of vessels), and leakage of fluid and blood into the tissues. Ultimately, this results in ๐ž๐๐ž๐ฆ๐š (fluid swelling) and multiple small hemorrhages throughout the body. In many cases, ๐ญ๐ก๐ซ๐จ๐ฆ๐›๐ข (blood clots) form in the damaged vessels, preventing bloodflow to tissues. These thrombi particularly seem to affect the heart muscle, causing tissue death and ultimately heart failure.

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
Diagnosis typically involves identifying the virus directly, through testing for its ๐‘๐๐€ (viral genome).

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ซ๐ž๐š๐ญ๐ž๐? ๐‡๐จ๐ฐ ๐ข๐ฌ ๐ฉ๐ซ๐ž๐ฏ๐ž๐ง๐ญ๐ž๐?
Unfortunately there is no specific treatment for bluetongue, other than supportive care. In some countries, this disease is considered ๐ซ๐ž๐ฉ๐จ๐ซ๐ญ๐š๐›๐ฅ๐ž, meaning that government officials must get involved to control the spread of disease. Prevention typically focuses on reducing exposure to midges, although vaccines are available in some countries.

๐๐ก๐จ๐ญ๐จ๐ฌ
1-4) Small hemorrhages throughout the body! Hemorrhages are characteristically found in the mouth, esophagus, and around the aorta.
5) A silly photo from when my friend and I made a pathology cake of a sheep with bluetongue virus! She also has orf infection, made of delicious cranberries.

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Lear AS. Bluetongue in ruminants. Merck Veterinary Manual 2022.

Photos 1-4 ยฉ Noahโ€™s Arkive contributors Allison, King licensed under CC BY-SA 4.0.

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