White Spotted Kidneys

Todayโ€™s path rounds are on ๐ฐ๐ก๐ข๐ญ๐ž ๐ฌ๐ฉ๐จ๐ญ๐ญ๐ž๐ ๐ค๐ข๐๐ง๐ž๐ฒ๐ฌ!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐–๐ก๐ข๐ญ๐ž ๐ฌ๐ฉ๐จ๐ญ๐ญ๐ž๐ ๐ค๐ข๐๐ง๐ž๐ฒ๐ฌ are a form of ๐ž๐ฆ๐›๐จ๐ฅ๐ข๐œ ๐ง๐ž๐ฉ๐ก๐ซ๐ข๐ญ๐ข๐ฌ. Nephritis means inflammation of the kidney, and embolic means that the inflammation is caused by ๐ž๐ฆ๐›๐จ๐ฅ๐ข or aggregates of bacteria in the bloodstream.

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
Any species can get this condition, however the name โ€œwhite spotted kidneysโ€ is typically used in cattle.

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
As mentioned, this type of nephritis is caused by emboli of bacteria flowing in the bloodstream. These bacteria will lodge in the small vessels of the kidney, and set up a home for themselves. The immune system doesnโ€™t like them very much, so they send ๐ฅ๐ž๐ฎ๐ค๐จ๐œ๐ฒ๐ญ๐ž๐ฌ (white blood cells) like macrophages and neutrophils to eat the bacteria. This inflammatory response produces an ๐š๐›๐ฌ๐œ๐ž๐ฌ๐ฌ (focal area of pus) that we can see on the surface of the kidney.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
Having a ๐›๐š๐œ๐ญ๐ž๐ซ๐ž๐ฆ๐ข๐š, or bacteria in the bloodstream, is often associated with a very sick animal. These bacteria can spread to any organ, forming abscesses, and severely compromising the animalโ€™s health. So while embolic nephritis can cause significant kidney damage, this is often overshadowed by damage to more โ€œimportantโ€ organs, like the heart, brain or lungs.

Typically, we think of this bacteremia occurring in very young calves with an infected umbilicus, which allows the bacteria direct entry into the bloodstream. If these calves survive their bacteremia, the abscesses in the kidney will heal by ๐Ÿ๐ข๐›๐ซ๐จ๐ฌ๐ข๐ฌ (forming scar tissue). Once resolved, these lesions generally do not bother the animal!

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
Embolic nephritis can be diagnosed at necropsy or at slaughter by seeing random white to yellow abscesses throughout the kidney! These lesions may also be visible on ultrasound in the live animal.

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ซ๐ž๐š๐ญ๐ž๐?
If the animal has an active bacteremia, an intense antibiotic protocol is warranted to help them get the infection under control. If the animal has already recovered, then no treatment is needed!

๐๐ก๐จ๐ญ๐จ๐ฌ
1-5) Examples of white spotted kidneys!

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Maxie, G. Jubb, Kennedy and Palmerโ€™s Pathology of Domestic Animals, Volume 2. Sixth Edition.

Photos 1-5 ยฉ Noahโ€™s Arkive contributors Williams, Jakowski, Acland, Metro licensed under CC BY-SA 4.0.

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