Plasma Cell Pododermatitis

Todayโ€™s path rounds are on ๐ฉ๐ฅ๐š๐ฌ๐ฆ๐š ๐œ๐ž๐ฅ๐ฅ ๐ฉ๐จ๐๐จ๐๐ž๐ซ๐ฆ๐š๐ญ๐ข๐ญ๐ข๐ฌ!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐๐ฅ๐š๐ฌ๐ฆ๐š ๐œ๐ž๐ฅ๐ฅ ๐ฉ๐จ๐๐จ๐๐ž๐ซ๐ฆ๐š๐ญ๐ข๐ญ๐ข๐ฌ is a rare condition that causes high numbers of ๐ฉ๐ฅ๐š๐ฌ๐ฆ๐š ๐œ๐ž๐ฅ๐ฅ๐ฌ (antibody producing cells) to accumulate in the tissues of the paws.

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
This disorder affects cats!

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
The cause of this disorder is currently unknown, however it has been linked to ๐Ÿ๐ž๐ฅ๐ข๐ง๐ž ๐ข๐ฆ๐ฆ๐ฎ๐ง๐จ๐๐ž๐Ÿ๐ข๐œ๐ข๐ž๐ง๐œ๐ฒ ๐ฏ๐ข๐ซ๐ฎ๐ฌ, with approximately 50% of cases testing positive for the virus. The condition itself is thought to be ๐ข๐ฆ๐ฆ๐ฎ๐ง๐ž-๐ฆ๐ž๐๐ข๐š๐ญ๐ž๐, meaning that some dysfunction of the immune system is the basic underlying cause.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
PCP begins as a non-painful swelling of the footpads of the paws, that eventually progresses to a scaly skin surface, followed by ulceration and bleeding. As the disease progresses, it becomes more and more painful for the cat, and eventually they are unwilling to walk because it is so ouchy! Poor kitties ๐Ÿ˜ญ

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
This disorder can be diagnosed based on the swollen footpads, combined with a ๐Ÿ๐ข๐ง๐ž ๐ง๐ž๐ž๐๐ฅ๐ž ๐š๐ฌ๐ฉ๐ข๐ซ๐š๐ญ๐ž (using a needle to sample cells) showing large numbers of plasma cells.

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ซ๐ž๐š๐ญ๐ž๐?
Unfortunately because the cause of the disease is unknown, developing a treatment plan can be difficult! These lesions have been shown to respond to ๐ข๐ฆ๐ฆ๐ฎ๐ง๐จ๐ฌ๐ฎ๐ฉ๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐ฏ๐ž medications, to reduce the immune-mediated reaction causing the problem. Additionally, these cats can benefit greatly from some pain medication to help with their sore feet!

๐๐ก๐จ๐ญ๐จ๐ฌ
1-4) Examples of ouchy kitty paws with plasma cell pododermatitis ๐Ÿ˜ญ

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Maxie, G. Jubb, Kennedy and Palmerโ€™s Pathology of Domestic Animals, Volume 1. Sixth Edition.

Photos 1-2 ยฉ Julia Case.
Photos 3-4 ยฉ Noahโ€™s Arkive contributor Williams, Grandi licensed under CC BY-SA 4.0.

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