Category: Genetic

𝐔𝐫𝐨𝐥𝐢𝐭𝐡𝐢𝐚𝐬𝐢𝐬 is the presence of 𝐮𝐫𝐢𝐧𝐚𝐫𝐲 𝐜𝐚𝐥𝐜𝐮𝐥𝐢 (stones, basically) in the urinary passages, typically in the bladder or urethra. You can also get calculi in the kidney, called 𝐧𝐞𝐩𝐡𝐫𝐨𝐥𝐢𝐭𝐡𝐬, as part of the same disease process. The stones are made up of precipitated urine contents, proteins and debris, which clump together and can obstruct normal flow of urine.

You may have heard of this condition referred to as 𝐄𝐡𝐥𝐞𝐫𝐬-𝐃𝐚𝐧𝐥𝐨𝐬 𝐬𝐲𝐧𝐝𝐫𝐨𝐦𝐞 in people. Basically, it is a condition where 𝐜𝐨𝐥𝐥𝐚𝐠𝐞𝐧, the major structural protein found in the skin and joints has an abnormality in the shape or size of its fibers, preventing them from linking together properly to provide strength to the skin.