Arthrogryposis

Todayโ€™s path rounds are on ๐š๐ซ๐ญ๐ก๐ซ๐จ๐ ๐ซ๐ฒ๐ฉ๐จ๐ฌ๐ข๐ฌ!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐€๐ซ๐ญ๐ก๐ซ๐จ๐ ๐ซ๐ฒ๐ฉ๐จ๐ฌ๐ข๐ฌ literally means crooked joint, which is a pretty accurate description of this disease! In this condition, an animal is born with joints that cannot straighten, and occasionally entire limbs that cannot straighten.

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
Any species can get this!

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
Unfortunately the cause of this condition is often unclear, but it is thought to be related to decreased limb movement while in the womb. The underlying issue is improper development of the nerves supplying muscles in the limbs, preventing normal movement and muscular development. This improper nerve development may be genetic, linked to toxin ingestion or viral infection of the mother, or it may just be a sporadic disease that pops up without any specific cause.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
Unfortunately these animals are often unable to walk or stand, due to their improper nerve development and crooked joints. Thus, they cannot nurse to receive ๐œ๐จ๐ฅ๐จ๐ฌ๐ญ๐ซ๐ฎ๐ฆ, the motherโ€™s first milk which contains high levels of antibodies that allows the baby to respond to infections.

Additionally, arthrogryposis is often associated with other severe musculoskeletal abnormalities like ๐ฌ๐œ๐จ๐ฅ๐ข๐จ๐ฌ๐ข๐ฌ (sideways curving of the spine), ๐ค๐ฒ๐ฉ๐ก๐จ๐ฌ๐ข๐ฌ (rounding of the spine) or ๐ญ๐จ๐ซ๐ญ๐ข๐œ๐จ๐ฅ๐ฅ๐ข๐ฌ (twisting of the neck).

These animals are often euthanized because there is no known treatment for this condition.

๐๐ก๐จ๐ญ๐จ๐ฌ
1-5) Examples of crooked joints in pigs and calves! But remember, any species, even humans, can get this condition.

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Maxie, G. Jubb, Kennedy and Palmerโ€™s Pathology of Domestic Animals, Volume 1. Sixth Edition.

Photos 1-5 courtesy of Noahโ€™s Arkive.

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