Orf

Todayโ€™s path rounds are on ๐จ๐ซ๐Ÿ!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐Ž๐ซ๐Ÿ is viral disease that can be found throughout the world! It also goes by the names ๐œ๐จ๐ง๐ญ๐š๐ ๐ข๐จ๐ฎ๐ฌ ๐ž๐œ๐ญ๐ก๐ฒ๐ฆ๐š or ๐œ๐จ๐ง๐ญ๐š๐ ๐ข๐จ๐ฎ๐ฌ ๐ฉ๐ฎ๐ฌ๐ญ๐ฎ๐ฅ๐š๐ซ ๐๐ž๐ซ๐ฆ๐š๐ญ๐ข๐ญ๐ข๐ฌ.

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
This disease is classically seen in sheep and goats, however it can infect many other animals. It can even infect humans who are handling infected animals.

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
Orf is caused by a ๐ฉ๐š๐ซ๐š๐ฉ๐จ๐ฑ๐ฏ๐ข๐ซ๐ฎ๐ฌ, which infects ๐ž๐ฉ๐ข๐๐ž๐ซ๐ฆ๐š๐ฅ ๐œ๐ž๐ฅ๐ฅ๐ฌ (skin cells) by entering small wounds in the skin. Typically, this infection occurs first around the lips after the animal eats rough or scratchy feed, allowing the virus to enter the skin. From there, the virus can spread to the eyes and muzzle. Once the virus has infected the epidermis, it produces a ๐ ๐ซ๐จ๐ฐ๐ญ๐ก ๐Ÿ๐š๐œ๐ญ๐จ๐ซ that causes the skin cells to proliferate rapidly. This produces the crusty, raised lesions that are characteristic of the disease.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
Unfortunately, these scabby lesions can be quite painful for the animal! In some cases, they may even stop eating due to the pain, leading to weight loss and even starvation. This is particularly true in lambs, who will not drink enough milk to maintain their growing body.

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
The crusting lesions around the mouth are characteristic of the disease, so often no further diagnostic tests are needed. However, in some unusual looking cases, the veterinarian might conduct a ๐๐‚๐‘ ๐ญ๐ž๐ฌ๐ญ to directly identify the virusโ€™ DNA to confirm the disease.

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ซ๐ž๐š๐ญ๐ž๐? ๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ฉ๐ซ๐ž๐ฏ๐ž๐ง๐ญ๐ž๐?
Unfortunately there is no specific treatment for this disease, other than simply allowing the animalโ€™s immune system to kick in. This can take 1-4 weeks to clear the infection. In the mean time, it is important to quarantine the animal away from other animals, and use caution when handling the animal due to the zoonotic risk.

Thankfully, there is now a vaccine for this disease! However, it is a ๐ฅ๐ข๐ฏ๐ž ๐ฏ๐š๐œ๐œ๐ข๐ง๐ž, which means it works by giving the animal the disease and allowing it to recover. This is important to know, because these animals must be quarantined away from unvaccinated animals, and must be handled with appropriate biosecurity measures.

๐๐ก๐จ๐ญ๐จ๐ฌ
1-5) Crusty sheep and goats with orf.

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Maxie, G. Jubb, Kennedy and Palmerโ€™s Pathology of Domestic Animals, Volume 1. Sixth Edition.
Scott PR. Overview of contagious ecthyma. Merck Veterinary Manual 2016.

Photos 1-5 ยฉ Noahโ€™s Arkive contributors King, Nuehring, Luginbuhl, Mosier, McGavin licensed under CC BY-SA 4.0.

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