Multilobed Gall Bladders

A quick, fun pathology for your Monday! Todayโ€™s path rounds are on ๐ฆ๐ฎ๐ฅ๐ญ๐ข๐ฅ๐จ๐›๐ž๐ ๐ ๐š๐ฅ๐ฅ ๐›๐ฅ๐š๐๐๐ž๐ซ๐ฌ!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
The ๐ ๐š๐ฅ๐ฅ ๐›๐ฅ๐š๐๐๐ž๐ซ is a big sac hanging out next to the liver, which stores ๐›๐ข๐ฅ๐ž. Bile is a product of the liver that contains digestive enzymes to break down fats. Usually the gall bladder is only one โ€œlobeโ€ or sac, but in some cases there can be multiple!

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
We see this in cats! A recent study showed that 14% of cats have bilobed gall bladders. Neat ๐Ÿ˜ป

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
Having multiple lobes is thought to be a developmental anomaly, meaning that it occurs when the liver is forming. The reason for the anomaly occurring is unknown.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
In the vast majority of cases, a multilobed gall bladder is an ๐ข๐ง๐œ๐ข๐๐ž๐ง๐ญ๐š๐ฅ ๐Ÿ๐ข๐ง๐๐ข๐ง๐ , meaning we accidentally come across it while weโ€™re looking for something else. In some cases, the multilobed gall bladder can develop gall stones or inflammation.

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
This anomaly can be diagnosed using ultrasound, usually while the cat is being examined for another issue. It can also be seen at necropsy.

๐๐ก๐จ๐ญ๐จ๐ฌ
1-3) Some bilobed gall bladders! One of the cases has a ๐ ๐š๐ฅ๐ฅ ๐›๐ฅ๐š๐๐๐ž๐ซ ๐œ๐š๐ซ๐œ๐ข๐ง๐จ๐ฆ๐š (malignant tumour of the gall bladder) in one lobe, with a normal second lobe.
4) A rare trilobed gall bladder!

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Maxie, G. Jubb, Kennedy and Palmerโ€™s Pathology of Domestic Animals, Volume 2. Sixth Edition.
Spain HN, Penninck DG, Thelen M. Ultrasonographic prevalence and proposed morphologic classification of bilobed gallbladder in cats. J Feline Med Surg 2021.

Photos 1-2 ยฉ Noahโ€™s Arkive contributor Rech, Domingo licensed under CC BY-SA 4.0.
Photos 3-4 ยฉ University of Calgary Diagnostic Services Unit.

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