Cryptorchidism

Todayโ€™s path rounds are on ๐œ๐ซ๐ฒ๐ฉ๐ญ๐จ๐ซ๐œ๐ก๐ข๐๐ข๐ฌ๐ฆ!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐‚๐ซ๐ฒ๐ฉ๐ญ๐จ๐ซ๐œ๐ก๐ข๐๐ข๐ฌ๐ฆ is the most common disorder of sexual development in male animals. During development, the testicles are located near the kidneys, and as the animal develops, they are pulled downwards into the scrotum, their normal home. In cryptorchidism, one or both of the testicles doesnโ€™t reach its final destination, and ends up somewhere in the abdomen!

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
Any species can get this!

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
The descent of the testicles is actually very complex, and involves a lot of genes, hormones, and structural development. So an abnormality in any of these aspects, or even some environmental factors, can lead to development of cryptorchidism. That said, a hereditary component has been established in pretty much every species, and is believed to be the most common cause of this disorder. Therefore, cryptorchid animals should not be bred, to hopefully prevent future cryptorchids!

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
Generally it isnโ€™t a huge issue having a testicle in the abdomen. However, it does predispose the animal to some potentially serious conditions! Cryptorchid testicles have an increased risk of developing tumours, particularly in dogs. They are also at a greater risk of ๐ญ๐ž๐ฌ๐ญ๐ข๐œ๐ฎ๐ฅ๐š๐ซ ๐ญ๐จ๐ซ๐ฌ๐ข๐จ๐ง (twisting of the spermatic cord compromising blood flow) which can cause ๐ง๐ž๐œ๐ซ๐จ๐ฌ๐ข๐ฌ (cell death) of the testicle and be a source of pretty serious inflammation!

Interestingly, cryptorchid testicles do not produce sperm! This is because the cells that complete ๐ฌ๐ฉ๐ž๐ซ๐ฆ๐š๐ญ๐จ๐ ๐ž๐ง๐ž๐ฌ๐ข๐ฌ (sperm production) are very temperature sensitive, and the abdomen is just too warm for them to complete their normal functions. Cool!

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
This is usually pretty easy to diagnose: simply palpate the scrotum to see if you can feel two testicles! If you canโ€™t, then thereโ€™s a good chance that the animal is a cryptorchid. A word of warning however: some animal species are not born with their testes descended, so if you are dealing with one of those species, make sure the animal is an appropriate age before you diagnose it as a cryptorchid!

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ซ๐ž๐š๐ญ๐ž๐?
As mentioned before, these animals should not breed, so cryptorchidism is usually โ€œtreatedโ€ by ๐œ๐š๐ฌ๐ญ๐ซ๐š๐ญ๐ข๐จ๐ง (removal of the testicles). However, castrating a cryptorchid is a bit more complex than castrating normal animals, since you often have to open the abdomen to go searching for the missing testicle! Therefore, these castrations are usually a pretty intensive surgery, particularly for our large animal species like cattle and horses.

๐๐ก๐จ๐ญ๐จ๐ฌ
1-2) A normal sized testicle next to a cryptorchid testicle. Cryptorchid testicles are small because they arenโ€™t able to develop properly in the high temperature of the abdomen!
3-5) Examples of intra-abdominal cryptorchid testicles! Note that they can be found very close to the kidneys.

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Maxie, G. Jubb, Kennedy and Palmerโ€™s Pathology of Domestic Animals, Volume 3. Sixth Edition.

Photos 1-2 ยฉ University of Calgary Diagnostic Services Unit.
Photos 3-5 ยฉ Noahโ€™s Arkive contributors Crowell, Niyo, Loukopoulos licensed under CC BY-SA 4.0.

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