Lymphocystis

Todayโ€™s path rounds are on ๐ฅ๐ฒ๐ฆ๐ฉ๐ก๐จ๐œ๐ฒ๐ฌ๐ญ๐ข๐ฌ!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐‹๐ฒ๐ฆ๐ฉ๐ก๐จ๐œ๐ฒ๐ฌ๐ญ๐ข๐ฌ is a viral infection that produces large, cauliflower-like masses on the skin of fish. In fact, it is the most common viral infection of aquarium fish!

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
This disease affects some species of ๐ญ๐ž๐ฅ๐ž๐จ๐ฌ๐ญ fish, which are the ray-finned fish. Both freshwater and marine species are affected!

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
As mentioned, this is a viral infection, caused by a type of ๐ข๐ซ๐ข๐๐จ๐ฏ๐ข๐ซ๐ฎ๐ฌ called ๐‹๐ฒ๐ฆ๐ฉ๐ก๐จ๐œ๐ฒ๐ฌ๐ญ๐ข๐ฏ๐ข๐ซ๐ฎ๐ฌ. There are many different viruses within this family, with each identified virus affecting different groups of fish species. It is believed that the virus is transmitted when the masses rupture or shed cells, releasing the virus into the water, where it attaches to and infects other fish in the area.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
Thankfully, this disease is considered ๐ฌ๐ž๐ฅ๐Ÿ-๐ฅ๐ข๐ฆ๐ข๐ญ๐ข๐ง๐ , meaning that it wonโ€™t continue to develop or cause additional problems in the fish. In some cases, the masses may eventually disappear entirely. However, the masses caused by lymphocystis can be quite disfiguring, and make the fish look ugly. No one wants to buy an ugly fish, so often this disease is only problematic in terms of economics!

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
Often the veterinarian will suspect this disease just based on how it looks, however to confirm the diagnosis ๐ก๐ข๐ฌ๐ญ๐จ๐ฅ๐จ๐ ๐ฒ (looking at the tissue under the microscope) needs to be performed. On histology, the pathologist will see huge ๐Ÿ๐ข๐›๐ซ๐จ๐›๐ฅ๐š๐ฌ๐ญ๐ฌ (cells that produce fibrous tissue) that contain ๐ข๐ง๐œ๐ฅ๐ฎ๐ฌ๐ข๐จ๐ง ๐›๐จ๐๐ข๐ž๐ฌ. These inclusion bodies are actually aggregates of proteins that the virus has produced!

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ซ๐ž๐š๐ญ๐ž๐? ๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ฉ๐ซ๐ž๐ฏ๐ž๐ง๐ญ๐ž๐?
Unfortunately there is no treatment for lymphocystis. Fish keepers will often isolate affected fish from the others to prevent spread of the disease. Prevention of the disease typically involves maintaining good hygiene and keeping a low stress environment.

๐๐ก๐จ๐ญ๐จ๐ฌ
1-5) Examples of fish with lymphocystis lesions.
6) What lymphocystis looks like under the microscope!

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Noga, EJ. Fish Disease: Diagnosis and Treatment. 2010.

Photos 1-6 ยฉ Noahโ€™s Arkive contributors King, Jakowski, Metro, Render, Wolfe licensed under CC BY-SA 4.0.

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