Gall Bladder Mucocele

Todayโ€™s path rounds are on ๐ ๐š๐ฅ๐ฅ ๐›๐ฅ๐š๐๐๐ž๐ซ ๐ฆ๐ฎ๐œ๐จ๐œ๐ž๐ฅ๐ž! This post is inspired by a case I had this week!

๐–๐ก๐š๐ญ ๐ข๐ฌ ๐ข๐ญ?
๐†๐š๐ฅ๐ฅ ๐›๐ฅ๐š๐๐๐ž๐ซ ๐ฆ๐ฎ๐œ๐จ๐œ๐ž๐ฅ๐ž is a condition where the ๐ ๐š๐ฅ๐ฅ ๐›๐ฅ๐š๐๐๐ž๐ซ, the storage sac for bile from the liver, becomes full of mucus-like bile instead of the normal fluid bile!

๐–๐ก๐จ ๐ ๐ž๐ญ๐ฌ ๐ข๐ญ?
This condition affects dogs, particularly older dogs that have ๐ž๐ง๐๐จ๐œ๐ซ๐ข๐ง๐จ๐ฉ๐š๐ญ๐ก๐ข๐ž๐ฌ (diseases of endocrine system).

๐–๐ก๐š๐ญ ๐œ๐š๐ฎ๐ฌ๐ž๐ฌ ๐ข๐ญ?
Unfortunately, the inciting cause of the mucus accumulation is unknown, and may be due to multiple factors. Some proposed risk factors include decreased motility of the gall bladder wall, high-fat diets or steroid therapy.

๐–๐ก๐ฒ ๐ข๐ฌ ๐ญ๐ก๐ข๐ฌ ๐š ๐ฉ๐ซ๐จ๐›๐ฅ๐ž๐ฆ?
Having a bunch of sludge in the gall bladder can block proper bile flow, leading to ๐œ๐ก๐จ๐ฅ๐ž๐ฌ๐ญ๐š๐ฌ๐ข๐ฌ (stopped bile flow). This cause ๐›๐ข๐ฅ๐ž ๐š๐œ๐ข๐๐ฌ, the main component of bile, to accumulate within the animal. This can cause vomiting, diarrhea, fever and ๐ข๐œ๐ญ๐ž๐ซ๐ฎ๐ฌ (yellowing of the tissue). The abdomen can also become very painful, thanks to having an overly large gall bladder with a very stretched wall! Stopping bile flow can also allow bacteria to migrate through the bile tracts into the liver, causing a ๐ก๐ž๐ฉ๐š๐ญ๐ข๐ญ๐ข๐ฌ (inflammation of the liver).

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐๐ข๐š๐ ๐ง๐จ๐ฌ๐ž๐?
Diagnosis is typically done on ultrasound, where the gall bladder has a characteristic โ€œkiwiโ€ appearance.

๐‡๐จ๐ฐ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ซ๐ž๐š๐ญ๐ž๐?
Treatment typically involves ๐œ๐ก๐จ๐ฅ๐ž๐œ๐ฒ๐ฌ๐ญ๐ž๐œ๐ญ๐จ๐ฆ๐ฒ, where the gall bladder is removed. This is the best route of treatment because it prevents the gall bladder from rupturing if alternative treatments do not work quick enough. These dogs should also receive antibiotics to prevent or treat secondary infection of the liver.

๐๐ก๐จ๐ญ๐จ๐ฌ
1) A seriously enlarged gall bladder at necropsy!
2-5) Examples of what the mucinous accumulation in the gall bladder looks like.

๐’๐จ๐ฎ๐ซ๐œ๐ž๐ฌ
Center SA. Canine Gallbladder Mucocele. Merck Veterinary Manual, 2016.

Photos 2-3 ยฉ University of Calgary Diagnostic Services Unit.
Photos 1, 4-5 ยฉ Noahโ€™s Arkive contributors Berkowitz, Vet Biosciences, Morris licensed under CC BY-SA 4.0.

Leave a Reply